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Pneumoniae is associated with symptomatic sore throat because of diagnostic test limitations. Currently, antibiotic treatment is only recommended for Streptococcus pyogenes (group A streptococcal) pharyngitis, and treatment is mainly to prevent development of serious postinfectious syndromes like rheumatic fever. There is no clinical indication at this time to seek or empirically treat C. pneumoniae in patients with sore throat. Epidemiology Based on MIF and culture studies, C. pneumoniae appears to be a common human respiratory pathogen.

Martin, D. H. 2008. Urethritis in males, p. 1107– 1126. In K. K. Holmes, P. F. Sparling, W. E. Stamm, P. Piot, J. N. Wasserheit, L. Corey, M. S. Cohen, and D. H. ), Sexually Transmitted Diseases, 4th ed. McGraw Hill Medical, New York, NY. Meyers, D. , H. Halvorson, and S. Luckhaupt. 2007. S. Preventive Services Task Force. Ann. Intern. Med. 147:135–142. Miller, W. C. 2008. Epidemiology of chlamydial infection: are we losing ground? Sex. Transm. Infect. 84:82–86. Miller, W. , and E. M. Ko. 2011.

Can newer antibiotics with greater activity and longer pharmacologic half-lives reduce treatment failures and perhaps even prevent early reinfections, and at least partly address the important issue of reinfection? Currently, preventing repeated genital infection depends on notifying sex partners; in practice, it is extraordinarily difficult to identify and treat the majority of partners. Mass treatment of trachoma reduces the burden of active disease in a community or district and in so doing reduces the probability of reinfection.

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